Antibodies Signal Transduction

Phospho Ezrin (Thr567) Antibodyis available at Gentaur for Next week Delivery. Description: The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein...

Anti-Calponin-1 Rabbit Monoclonal Antibodyis available at Gentaur for Next week Delivery. Description: Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist; a 34kDa form and a 29kDa form...

Anti-Cytokeratin-8 Rabbit Monoclonal Antibodyis available at Gentaur for Next week Delivery. Description: Keratin 8 belongs to the type B (basic) subfamily of high molecular weight keratins and exists in combination with keratin 18. Keratin 8 is...

Anti-PTEN Rabbit Monoclonal Antibodyis available at Gentaur for Next week Delivery. Description: PTEN, a tumor suppressor, has been implicated in a large number of human tumors and is conserved from humans to worms. Characterization of PTEN protein...

Anti-Aurora B Rabbit Monoclonal Antibodyis available at Gentaur for Next week Delivery. Description: The serine/threonine protein kinase aurora B (Aurora B) is a chromosomal passenger protein critical for accurate chromosome segregation, cytokinesis,...

Anti-Smad4 Rabbit Monoclonal Antibodyis available at Gentaur for Next week Delivery. Description: Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad), have been implicated as downstream effectors of TGFβ/BMP signaling...

Anti-mTOR Rabbit Monoclonal Antibody is available at Gentaur for Next week Delivery. Description: The mammalian target of rapamycin (mTOR, FRAP, RAFT) is a Ser/Thr protein kinase that functions as an ATP and amino acid sensor to balance nutrient...

Anti-DCAMKL2 Antibodyis available at Gentaur for Next week Delivery. Description: Protein kinase with a significantly reduced C(a2+)/CAM affinity and dependence compared to other members of the CaMK family. May play a role in the down-regulation of...

Anti-Manic Fringe Antibodyis available at Gentaur for Next week Delivery. Description: Glycosyltransferase involved in the elongation of O-linked ligands to activate Notch signaling. Possesses fucose-specific beta-1,3-N-acetylglucosaminyltransferase...

Anti-PPP4C Antibody (2F11-D10-G4)is available at Gentaur for Next week Delivery. Description: Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA...

Anti-PRMT4 Antibody (2B9-H11-H10)is available at Gentaur for Next week Delivery. Description: Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins...

Anti-DCTN1 Antibody (3D5-C6-D5)is available at Gentaur for Next week Delivery. Description: Plays a key role in dynein-mediated retrograde transport of vesicles and organelles along microtubules by recruiting and tethering dynein to microtubules. Binds...

Anti-WDR77 Antibody (8A10-C10-E8)is available at Gentaur for Next week Delivery. Description: Non-catalytic component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm...

Anti-SMAD5 Antibody (4B10-B10-B6)is available at Gentaur for Next week Delivery. Description: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). Immunogen...

Anti-SMC1A Antibody (4C5-C8-A11)is available at Gentaur for Next week Delivery. Description: Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of...

Anti-KIAA1967 Antibody (3G4-D11-D7)is available at Gentaur for Next week Delivery. Description: Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and...

Anti-Hexokinase 1 Antibody (6B8-G11-E7)is available at Gentaur for Next week Delivery. Description: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form...

Anti-Mannose Phosphate Isomerase Antibody (4G9-B4-B8)is available at Gentaur for Next week Delivery. Description: Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in...

Anti-PPP1A Antibody (1C11-C10-H5-E9)is available at Gentaur for Next week Delivery. Description: Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological...

Anti-Hexokinase II Antibody (1E8-H3-F11)is available at Gentaur for Next week Delivery. Description: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the...

Anti-DsbA Antibody (1A2-D4-G10)is available at Gentaur for Next week Delivery. Description: Required for disulfide bond formation in some periplasmic proteins such as PhoA or OmpA. Acts by transferring its disulfide bond to other proteins and is reduced...

Anti-CBR1 Antibody (2C9-B12-C4)is available at Gentaur for Next week Delivery. Description: NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins,...

Anti-TXNRD2 Antibody (3F2-E12-F10)is available at Gentaur for Next week Delivery. Description: Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox-regulated cell signaling Immunogen...

Anti-Pyruvate Dehydrogenase E1-α subunit Antibody (3H2-F8-B5)is available at Gentaur for Next week Delivery. Description: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2, and thereby links the...

Anti-GPT2/ALT2 Antibodyis available at Gentaur for Next week Delivery. Description: Alanine aminotransferase 2 catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Immunogen Sequence:KLH-conjugated...

Phospho-C/EBP β (Thr235) Antibodyis available at Gentaur for Next week Delivery. Description: Important transcription factor regulating the expression of genes involved in immune and inflammatory responses. Plays also a significant role in adipogenesis,...

Phospho-Calnexin (Ser583) Antibodyis available at Gentaur for Next week Delivery. Description: Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in...

Phospho-ASK 1 (Ser83) Antibodyis available at Gentaur for Next week Delivery. Description: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular...

Phospho-AP-1 (Ser63) Antibodyis available at Gentaur for Next week Delivery. Description: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to...

Phospho-AMPKβ1 (Ser182) Antibodyis available at Gentaur for Next week Delivery. Description: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In...

Phospho-AMPKα1 (Ser496) Antibodyis available at Gentaur for Next week Delivery. Description: Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In...

Phospho-Akt1 (Ser246) Antibodyis available at Gentaur for Next week Delivery. Description: The serine/threonine kinase Akt family contains several members, including Akt1 (also designated PKB or RacPK), Akt2 and Akt 3, which exhibit sequence homology...

Anti-WFDC5 Antibodyis available at Gentaur for Next week Delivery. Description: WFDC5 is a member of the WAP-type four-disulfide core (WFDC) domain family. Most WFDC proteins contain only one WFDC domain, whereas WFDC5 contains two WFDC domains. The WFDC...

Anti-PIP5K Antibodyis available at Gentaur for Next week Delivery. Description: The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the phosphorylation of...

Anti- ALPK1 Antibodyis available at Gentaur for Next week Delivery. Description: Kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical conformation Immunogen Sequence:KLH-conjugated synthetic peptide...

Anti-IDH3 gamma Antibodyis available at Gentaur for Next week Delivery. Description: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes...

Anti-ZNT2 Antibodyis available at Gentaur for Next week Delivery. Description: The zinc (Zn) transporter ZNT2 (SLC30A2) is expressed in specialized secretory cells including breast, pancreas and prostate, and imports Zn into mitochondria and vesicles...

Anti-ZNF600 Antibodyis available at Gentaur for Next week Delivery. Description: Zinc-finger protein X-linked (ZFX) is a transcription factor required for self-renewal of embryonic stem cells. It has been implicated in the initiation and progression of...

Anti-Tensin 3 Antibodyis available at Gentaur for Next week Delivery. Description: May play a role in actin remodeling. Involved in the dissociation of the integrin-tensin-actin complex. EGF activates TNS4 and down-regulates TNS3 which results in capping...

Anti-HER2 (c-erbB-2), Rabbit Monoclonal Antibodyis available at Gentaur for Next week Delivery. Description: HER2 gene encodes a cell-surface glycoprotein tyrosine kinase receptor with extensive homology to the epidermal growth factor receptor. HER2 is...

Phospho-AKT1 (Tyr474) polyconal Antibodyis available at Gentaur for Next week Delivery. Description: The serine/threonine kinase Akt family contains several members, including Akt1 (also designated PKB or RacPK), Akt2 and Akt 3, which exhibit sequence...

UR144/XLR11, Synthetic Cannabinoids Antibodyis available at Gentaur for Next week Delivery. Description: Cannabinoids are a class of diverse chemical compounds that activate cannabinoid receptors on cells that repress neurotransmitter release in the...

JWH-250, Synthetic Cannabinoid Antibodyis available at Gentaur for Next week Delivery. Description: Cannabinoids are a class of diverse chemical compounds that activate cannabinoid receptors on cells that repress neurotransmitter release in the brain...

K2/spice, Synthetic Cannabinoids Antibodyis available at Gentaur for Next week Delivery. Description: Cannabinoids are a class of diverse chemical compounds that activate cannabinoid receptors on cells that repress neurotransmitter release in the brain...

BACE2/Asp1 Antibodyis available at Gentaur for Next week Delivery. Description: Accumulation of the amyloid-beta (Abeta) plaque in the cerebral cortex is a critical event in the pathogenesis of Alzheimer's disease. Abeta peptide is generated by...

Anti-Human Amyloid Beta 1-17 Antibody (Clone C4D10)is available at Gentaur for Next week Delivery. Description: Amyloid Beta (Aβ or Abeta) is a multi-functional peptide of 36-43 amino acids, processed from the Amyloid Precursor Protein (APP). It is most...

DAP1 Antibodyis available at Gentaur for Next week Delivery. Description: Death Associated Protein 1 (DAP1) is a 15 kDa protein that functions as a positive mediator of cell death initiated by interferon-gamma. The DAP1 protein is praline-rich and...

Phospho-ASK1 (Ser83) Antibodyis available at Gentaur for Next week Delivery. Description: ASK1 (Apoptosis Signal-regulating Kinase 1) activates two different subgroups of MAPKK, MKK4 and MKK6, which in turn activate c-Jun N-terminal Kinase (JNK) and p38...

Phospho-Caveolin-1 (Tyr14) Antibodyis available at Gentaur for Next week Delivery. Description: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By...

Phospho-Akt2 (Ser474) Antibodyis available at Gentaur for Next week Delivery. Description: AKT2 is a putative oncogenic protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. Furthermore, AKT2 was...