Anti-IDH3 gamma Antibody

Anti-IDH3 gamma Antibodyis available at Gentaur for Next week Delivery.

Description: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia. Several alternatively spliced transcript variants of this gene have been described, but only some of their full length natures have been determined

Immunogen Sequence:KLH-conjugated synthetic peptide encompassing a sequence within the center region of human IDH3

Target Alternative Name:Isocitrate dehydrogenase [NAD] subunit gamma mitochondrial; Isocitric dehydrogenase subunit gamma; NAD(+)-specific ICDH subunit gamma

Species Reactivities:Human, Mouse, Rat

Tag Line:Polyclonal antibody to detect endogenous levels of IDH3 in human, mouse and rat.

Formulation:In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide

Purification: Affinity purified

Application:WB

Positive Control:WB: MCF7, mouse heart, rat heart lysate

Application And Usages:WB; 1:500 – 1:2000

Handling:The antibody solution should be gently mixed before use