Anti-Human Amyloid Beta 1-17 Antibody (Clone C4D10)

Anti-Human Amyloid Beta 1-17 Antibody (Clone C4D10)is available at Gentaur for Next week Delivery.

Description: Amyloid Beta (Aβ or Abeta) is a multi-functional peptide of 36-43 amino acids, processed from the Amyloid Precursor Protein (APP). It is most commonly known to be associated with Alzheimer's disease since it is the main component of amyloid plaques found in the brains of the diseased subjects. However, it also plays a role in multiple non-disease activities including protection against metal-induced reactive oxidizing species (ROS), modification of cholesterol transport, and potential activity as a transcription factor. It is secreted by platelets into the blood serum and its levels elevate with age.

Immunogen Sequence:Synthetic peptide encoding amino acid residues 1-17 of Amyloid Beta protein.

Target Alternative Name:Amyloid beta A4 protein, ABPP, APPI, APP, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide (CVAP

Species Reactivities:Human. The 1-13 amino acid sequence of this protein is conserved in mice, rat, Humans and other species, so it might cross-interact with other species’ samples.

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Formulation:100 µg (0.5 mg/ml) in 1X PBS, pH 7.4 with 50% Glycerol.

Purification: Affinity purified

Application:Immunohistochemistry

Positive Control:Alzheimer disease brain tissue, frontal lobe

Application And Usages:Immunohistochemistry: 40 – 150 µg. However, optimal conditions must be determoned by the user.

Handling:The antibody solution should be gently mixed before use.