Anti-PPP4C Antibody (2F11-D10-G4)

Anti-PPP4C Antibody (2F11-D10-G4)is available at Gentaur for Next week Delivery.

Description: Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair.

Immunogen Sequence:Recombinant human Protein Phosphatase 4C protein fragments expressed in E.coli

Target Alternative Name:Pp4, Protein phosphatase X, PP-X, PPP4C, PPP4, PPX

Species Reactivities:Human

Tag Line:Monoclonal antibody to detect PPP4C

Formulation:In PBS (pH 7.4) containing with 0.02% sodium azide and 50% glycerol

Purification: Affinity purified

Application:WB, IF

Positive Control:WB: Hela and Jurkat cell lysates; IF: HeLa cells; IHC: human breast cancer tissue

Application And Usages:WB; 1:200, IF; 1:200

Handling:The antibody solution should be gently mixed before use