Phospho-ASK1 (Ser83) Antibody

Phospho-ASK1 (Ser83) Antibodyis available at Gentaur for Next week Delivery.

Description: ASK1 (Apoptosis Signal-regulating Kinase 1) activates two different subgroups of MAPKK, MKK4 and MKK6, which in turn activate c-Jun N-terminal Kinase (JNK) and p38 MAP Kinase. ASK1 is activated by TNFR and Fas through the interaction with members of the TRAF Family and the Fas-associated protein Daxx. Overexpression of ASK1 induces apoptosis. However, a catalytically inactive form of ASK1 has been shown to inhibit TNF-α induced apoptosis.

Immunogen Sequence:Synthesized peptide derived from human ASK 1 around the phosphorylation site of S83, (20-100aa)

Target Alternative Name:Mitogen-activated protein kinase kinase kinase 5, Apoptosis signal-regulating kinase 1, MAPK/ERK kinase kinase 5, MEK kinase 5, MEKK 5

Species Reactivities:Human

Tag Line:Polyclonal antibody to detect endogenous levels of ASK 1 protein only when phosphorylated at S83 in human.

Formulation:In PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Purification: Affinity-chromatography using epitope-specific immunogen

Application:WB, ELISA, IHC

Positive Control:WB: 293 cells

Application And Usages:WB 1:500-1:2000; ELISA 1:5000-1:20000; IHC 1:100-1:300

Handling:The antibody solution should be gently mixed before use