Human CellExp™ PD-L2 / B7-DC, mouse recombinant

Human CellExp™ PD-L2 / B7-DC, mouse recombinant is available at Gentaur for Next week delivery.

A protein involved in the costimulatory signal essential for T-cell proliferation.

Biomolecule/Target: PD-L2

Alternates names: PDL2, PD-L2, Butyrophilin B7-DC, CD273, PDCD1 ligand 2, PDCD1L2, PDCD1LG3

Synonyms: PDL2, PD-L2, Butyrophilin B7-DC, CD273, PDCD1 ligand 2, PDCD1L2, PDCD1LG2

Background Information: Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

Reconstitution Instructions: Reconstitute in sterile deionized water to a concentration of 50 μg/ml.

NCBI Gene Symbol: Pdcd1lg2

Gene ID: 58205

NCBI Accession: Q9WUL5