Human CellExp™ B7-H3 / CD276, Mouse recombinant

Human CellExp™ B7-H3 / CD276, Mouse recombinant is available at Gentaur for Next week delivery.

Regulate the T-cell-mediated immune response and a protective role in tumor cells by inhibiting natural-killer mediated cell lysis. Marker for detection of neuroblastoma cells.

Biomolecule/Target: CD276

Alternates names: B7-H3, CD276, B7 homolog 3

Synonyms: B7-H3, CD276, B7 homolog 3

Background Information: B7 homolog 3 (B7-H3), a member of the immunoglobulin superfamily, is also known CD276, which contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domains. B7-H3 may participate in the regulation of T-cell-mediated immune response. B7-H3 also plays a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. Furthermore, B7-H3 is involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. It could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy.

Reconstitution Instructions: Reconstitute in sterile deionized water to a concentration of 50 μg/ml.

NCBI Gene Symbol: CD276

Gene ID: 102657

NCBI Accession: Q8VE98