BioVision Proteins
Human CellExp™ B7-H3 / CD276, Human Recombinant
- SKU:
- P1388-50
Description
Human CellExp™ B7-H3 / CD276, Human Recombinant is available at Gentaur for Next week delivery.
Regulate the T-cell-mediated immune response and a protective role in tumor cells by inhibiting natural-killer mediated cell lysis. Marker for detection of neuroblastoma cells
Biomolecule/Target:
Alternates names: 4Ig-B7-H3, B7-H3, CD276, PSEC0249, UNQ309/PRO352, B7 homolog 3
Synonyms: 4Ig-B7-H3, B7-H3, CD276, PSEC0249, UNQ309/PRO352, B7 homolog 3
Background Information: Human B7 homolog 3 (B7-H3) is a member of the B7 family of immune proteins that provide signals for the regulation of immune responses. Other family members include B7-1, B7-2, B7-H1/PD-L1, B7-H2, and PD-L2. B7 family proteins are type I transmembrane immunoglobulin (Ig) superfamily members that contain extracellular Ig V‑like and Ig C‑like domains with a short cytoplasmic tail. Termed 4IgB7-H3 or B7-H3b, this molecule has two additional Ig-like domains (one V‑type and one C‑type) and shows a ubiquituous expression pattern.
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile deionized water to a concentration of 100 µg/ml. Do not vortex. It is recommended to store at -20°C.
NCBI Gene Symbol: CD276
Gene ID: 80381
NCBI Accession: Q5ZPR3
Additional Information
Size: |
50 µg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
FAUX |
Source: |
HEK 293 cells |
Purity by SDS-PAGE: |
>95% as determined by SDS-PAGE. |
Endotoxin Level: |
Less than 1.0 EU per μg by the LAL method. |
Molecular Weight: |
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 48.5 kDa. The protein migrates as 65-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Appearance: |
Lyophilized powder |
Handling: |
Centrifuge the vial prior to opening. |