BioVision Products
Human CellExp™ PD-L1 /CD274 /B7-H1, human recombinant
- SKU:
- 7429-50
Description
Human CellExp™ PD-L1 /CD274 /B7-H1, human recombinant is available at Gentaur for Next week delivery.
Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner.
Biomolecule/Target: PD-L1 /CD274 /B7-H1
Alternates names: PD-L1, CD274, B7-H1, PDCD1L1, PDCD1LG1
Synonyms: PD-L1, CD274, B7-H1, PDCD1L1, PDCD1LG1
Background Information: Programmed cell death 1 ligand 1 (PD-L1) is also known as cluster of differentiation (CD274) or B7 homolog 1 (B7-H1). It has been identified as the ligand for PD1/PDCD1 (Cat. No. 7498) and has been demonstrated to play a role in the regulation of immune r
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
NCBI Gene Symbol: CD274
Gene ID: 29126
NCBI Accession: Q9NZQ7
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
HEK293 cells |
Purity by SDS-PAGE: |
?95% |
Assay: |
SDS-PAGE |
Purity: |
?90% |
Assay 2: |
HPLC |
Endotoxin Level: |
N/A |
Activity (Specifications/test method): |
Measured by its binding ability in a functional ELISA |
Biological activity: |
Immobilized Human PD-L1, His Tag at 5 ?g/mL (100 ?L/well) can bind Human PD-1, His Tag with a linear range of 0.15-1.25 ?g/mL. |
Results: |
N/A |
Molecular Weight: |
This protein is fused with polyhistidine tag at the C-terminus, has a calculated MW of 26.4 kDa. The predicted N-terminus is Phe 19. DTT-reduced Protein migrates as 35-40 kDa due to glycosylation. |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |