Human CellExp™ Nectin-4, Mouse Recombinant

Human CellExp™ Nectin-4, Mouse Recombinant is available at Gentaur for Next week delivery.

Transmembrane glycoprotein that involved in cell adhesion through trans-homophilic and -heterophilic interactions

Biomolecule/Target:

Alternates names: NECTIN4, LNIR, PRR4, PVRL4

Synonyms: NECTIN4, LNIR, PRR4, PVRL4

Background Information: Nectin-4 (gene name PVRL4, poliovirus receptor-like 4) is a 66 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. Nectins are cell adhesion molecules that play a key role in various biological processes such as polarity, proliferation, differentiation and migration, for epithelial, endothelial, immune and neuronal cells, during development and adult life. Nectin-4 is a tumor-associated antigen in 50%, 49% and 86%o of breast, ovarian and lung carcinomas, respectively, mostly on tumors of bad prognosis. Its expression is not detected in the corresponding normal tissues.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile deionized water to a concentration of 100 µg/ml. Do not vortex. It is recommended to store at -20°C.

NCBI Gene Symbol: NECTIN 4

Gene ID: 71740

NCBI Accession: Q8R007-1