BioVision Proteins
Human CellExp™ Nectin-4, Human Recombinant
- SKU:
- P1389-50
Description
Human CellExp™ Nectin-4, Human Recombinant is available at Gentaur for Next week delivery.
Transmembrane glycoprotein that involved in cell adhesion through trans-homophilic and -heterophilic interactions
Biomolecule/Target:
Alternates names: NECTIN4, LNIR, PRR4, PVRL4
Synonyms: NECTIN4, LNIR, PRR4, PVRL4
Background Information: Nectin-4 (gene name PVRL4, poliovirus receptor-like 4) is a 66 kDa type I transmembrane glycoprotein belonging to the Nectin family of Ig superfamily proteins. Nectins are cell adhesion molecules that play a key role in various biological processes such as polarity, proliferation, differentiation and migration, for epithelial, endothelial, immune and neuronal cells, during development and adult life. Nectin-4 is a tumor-associated antigen in 50%, 49% and 86%o of breast, ovarian and lung carcinomas, respectively, mostly on tumors of bad prognosis. Its expression is not detected in the corresponding normal tissues.
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile deionized water to a concentration of 100 µg/ml. Do not vortex. It is recommended to store at -20°C.
NCBI Gene Symbol: NECTIN4
Gene ID: 81607
NCBI Accession: Q96NY8
Additional Information
Size: |
50 µg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
FAUX |
Source: |
HEK 293 cells |
Purity by SDS-PAGE: |
>95% as determined by SDS-PAGE. |
Endotoxin Level: |
Less than 1.0 EU per μg by the LAL method. |
Molecular Weight: |
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 36.0 kDa. The protein migrates as 40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Appearance: |
Lyophilized protein |
Handling: |
Centrifuge the vial prior to opening. |