Human CellExp™ HDAC5, Catalytic Domain, Human Recombinant, Active

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SKU:
P1268-50
€185
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Description

Human CellExp™ HDAC5, Catalytic Domain, Human Recombinant, Active is available at Gentaur for Next week delivery.

Key epigenetic regulator

Biomolecule/Target: HDAC5

Alternates names: HDAC5, HD5, Histone Deacetylase 5, Antigen NY-CO-9, KIAA0600

Synonyms: HDAC5, HD5, Histone Deacetylase 5

Background Information: Human HDAC5 is composed of 1122 amino acid residues. The deacetylase domain of HDAC5 is located at the C-terminal half of the molecule. The N-terminal non-deacetylase domain does not show any significant homology with any published sequence. Both domains are required for HDAC5- mediated repression of gene transcription. HDAC5 interacts with a growing number of transcriptional factors including MEF2A as well as other HDAC proteins. The interacting complexes bind to specific regions of chromatin and regulate gene transcription in these regions.

Reconstitution Instructions: N/A

NCBI Gene Symbol: HDAC5

Gene ID: 10014

NCBI Accession: Q9UQL6

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
HEK293 cells
Purity by SDS-PAGE:
≥95%
Assay:
SEC
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
N/A
Activity (Specifications/test method):
Deacetylation activity was determined using the Boc-K(TFA)-AMC substrate.
Results:
N/A
Molecular Weight:
45 kDa
Storage Temperature:
-80°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Liquid
Handling:
Thaw on ice, and aliquot into smaller working quantities to avoid multiple freeze/thaw cycles.
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