Description
Human CellExp™ HDAC5, Catalytic Domain, Human Recombinant, Active is available at Gentaur for Next week delivery.
Key epigenetic regulator
Biomolecule/Target: HDAC5
Alternates names: HDAC5, HD5, Histone Deacetylase 5, Antigen NY-CO-9, KIAA0600
Synonyms: HDAC5, HD5, Histone Deacetylase 5
Background Information: Human HDAC5 is composed of 1122 amino acid residues. The deacetylase domain of HDAC5 is located at the C-terminal half of the molecule. The N-terminal non-deacetylase domain does not show any significant homology with any published sequence. Both domains are required for HDAC5- mediated repression of gene transcription. HDAC5 interacts with a growing number of transcriptional factors including MEF2A as well as other HDAC proteins. The interacting complexes bind to specific regions of chromatin and regulate gene transcription in these regions.
Reconstitution Instructions: N/A
NCBI Gene Symbol: HDAC5
Gene ID: 10014
NCBI Accession: Q9UQL6
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
HEK293 cells |
Purity by SDS-PAGE: |
≥95% |
Assay: |
SEC |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
N/A |
Activity (Specifications/test method): |
Deacetylation activity was determined using the Boc-K(TFA)-AMC substrate. |
Results: |
N/A |
Molecular Weight: |
45 kDa |
Storage Temperature: |
-80°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Liquid |
Handling: |
Thaw on ice, and aliquot into smaller working quantities to avoid multiple freeze/thaw cycles. |