BioVision Proteins
Human CellExp™ CD300c / LMIR2, Human Recombinant
- SKU:
- P1496-50
Description
Human CellExp™ CD300c / LMIR2, Human Recombinant is available at Gentaur for Next week delivery.
Present on monocytes, neutrophils, and some T and B lymphocytes
Biomolecule/Target:
Alternates names: CD300C, CLM-6, CMRF35-A1, CMRF-35, CMRF35A, IGSF16
Synonyms: CD300C, CLM-6, CMRF35-A1, CMRF-35, CMRF35A, IGSF16
Background Information: CMRF35-like molecule 6 (CLM-6) is also known as CD300 antigen-like family member C, CMRF35-A1, Immunoglobulin superfamily member 16 (IgSF16) , CD antigen CD300c, which belongs to the CD300 family. CLM-6 contains one Ig-like V-type (immunoglobulin-like) domain. CD300a/c RNA and surface expression were downregulated after stimulation of plasmacytoid dendritic cells (pDCs) with TLR7 and TLR9 ligands. Exogenous interferon (IFN)-alpha down-regulated CD300a/c expression. CD300a and CD300c play an important role in the cross-regulation of TNF-alpha and IFN-alpha secretion from pDCs. CD300a and CD300c are indistinguishable on the surface of NK cells.
Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.
NCBI Gene Symbol: CD300C
Gene ID: 10871
NCBI Accession: Q08708
Additional Information
Size: |
50 µg |
Adwords: |
False |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
True |
Source: |
HEK 293 cells |
Purity by SDS-PAGE: |
>95% |
Assay: |
SDS-PAGE |
Endotoxin Level: |
Less than 1.0 EU per μg by the LAL method. |
Molecular Weight: |
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 18.7 kDa. The protein migrates as 25-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Appearance: |
Lyophilized powder |
Handling: |
Centrifuge the vial prior to opening. |