BioVision Products
Human CellExp™ TPO, Human Recombinant
- SKU:
- 6483-50
Description
Human CellExp™ TPO, Human Recombinant is available at Gentaur for Next week delivery.
Stimulates the proliferation and maturation of megakaryocytes
Biomolecule/Target:
Alternates names: Megakaryocyte colony-stimulating factor, Myeloproliferative leukemia virus oncogene ligand, C-mpl ligand, ML, Megakaryocyte growth and development factor, MGDF, TPO, MKCSF, MPLLG, MGC163194, THPO.
Synonyms: Human Cellexp Human Recombinant TPO
Background Information: TPO (Thrombopoietin, also known as Mpl-ligand, MGDF), a glycoprotein hormone produced mainly by the liver and the kidney, stimulates the proliferation and maturation of megakaryocytes and promotes increased circulating levels of platelets in vivo. TPO signals through the c-mpl receptor and acts as an important regulator of circulating platelets.
Reconstitution Instructions: Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
NCBI Gene Symbol: THPO
Gene ID: 7066
NCBI Accession: P40225
Additional Information
Size: |
50 µg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
China |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
Human 293 cell expressed |
Purity by SDS-PAGE: |
> 95% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
< 1.0 EU per 1 μg of protein |
Activity (Specifications/test method): |
N/A |
Biological activity: |
ED₅₀ is typically 0.5 to 5 ng/mL. The specific activity was determined by the dose-dependent stimulation of the proliferation of human M07e cells |
Results: |
0.5 to 5 ng/ml |
Molecular Weight: |
80 to 85 kDa, monomer, glycosylated |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |