Human CellExp™ CD300c / LMIR2, Human Recombinant

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SKU:
P1496-50
€185
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Description

Human CellExp™ CD300c / LMIR2, Human Recombinant is available at Gentaur for Next week delivery.

Present on monocytes, neutrophils, and some T and B lymphocytes

Biomolecule/Target:

Alternates names: CD300C, CLM-6, CMRF35-A1, CMRF-35, CMRF35A, IGSF16

Synonyms: CD300C, CLM-6, CMRF35-A1, CMRF-35, CMRF35A, IGSF16

Background Information: CMRF35-like molecule 6 (CLM-6) is also known as CD300 antigen-like family member C, CMRF35-A1, Immunoglobulin superfamily member 16 (IgSF16) , CD antigen CD300c, which belongs to the CD300 family. CLM-6 contains one Ig-like V-type (immunoglobulin-like) domain. CD300a/c RNA and surface expression were downregulated after stimulation of plasmacytoid dendritic cells (pDCs) with TLR7 and TLR9 ligands. Exogenous interferon (IFN)-alpha down-regulated CD300a/c expression. CD300a and CD300c play an important role in the cross-regulation of TNF-alpha and IFN-alpha secretion from pDCs. CD300a and CD300c are indistinguishable on the surface of NK cells.

Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.

NCBI Gene Symbol: CD300C

Gene ID: 10871

NCBI Accession: Q08708

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Additional Information

Size:
50 µg
Adwords:
False
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
True
Source:
HEK 293 cells
Purity by SDS-PAGE:
>95%
Assay:
SDS-PAGE
Endotoxin Level:
Less than 1.0 EU per μg by the LAL method.
Molecular Weight:
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 18.7 kDa. The protein migrates as 25-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Storage Temperature:
-20°C
Shelf Life:
12 months
Appearance:
Lyophilized powder
Handling:
Centrifuge the vial prior to opening.
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