Human CellExp™ CD163, Human recombinant

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SKU:
9226-50
€185
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Description

Human CellExp™ CD163, Human recombinant is available at Gentaur for Next week delivery.

Scavenger receptor for the hemoglobin-haptoglobin complex

Biomolecule/Target: CD163

Alternates names: CD163, M130

Synonyms: CD163, M130

Background Information: Scavenger receptor cysteine-rich type 1 protein M130 (CD163) is also known as hemoglobin scavenger receptor, which is a scavenger receptor for the hemoglobin-haptoglobin complex. CD163 has also been shown to mark cells of monocyte/macrophage lineage. A soluble form of the receptor exists in plasma, commonly denoted sCD163. sCD163 is generated by ectodomain shedding of the membrane bound receptor. sCD163 is upregulated in a large range of inflammatory diseases including liver cirrhosis, type 2 diabetes, macrophage activation syndrome, Gaucher’s disease, sepsis, HIV infection, rheumatoid arthritis and Hodgkin Lymphoma.

Reconstitution Instructions: Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/ml

NCBI Gene Symbol: CD163

Gene ID: 9332

NCBI Accession: Q86VB7

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Additional Information

Size:
50 µg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
HEK 293 cells
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
≥95%
Assay 2:
N/A
Endotoxin Level:
< 1 EU/μg
Activity (Specifications/test method):
N/A
Biological activity:
N/A
Results:
N/A
Molecular Weight:
This protein is fused with a 6× His tag at C-terminus and has a calculated MW of 110.4 kDa. The protein migrates as 135-140 kDa in SDS-PAGE due to glycosylation.
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized
Handling:
Centrifuge the vial prior to opening.
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