Human CellExp™ CD27 Ligand/ CD70, Fc Tag, Mouse Recombinant

Human CellExp™ CD27 Ligand/ CD70, Fc Tag, Mouse Recombinant is available at Gentaur for Next week delivery.

Cytokine that binds to CD27 and plays role in T-cell activation.

Biomolecule/Target: CD70

Alternates names: CD70, CD27LG, TNFSF7, TNFSF7G, CD27L

Synonyms: CD70, CD27LG, TNFSF7, TNFSF7G, CD27L

Background Information: Cluster of Differentiation 70 (CD70) is also known as CD27 ligand (CD27L / CD27LG), TNFSF7, TNFSF7G, is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and is a surface antigen found on activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its receptor CD27 induces in priming, effector functions, differentiation and memory formation of T-cells, and thus is invloved in the biological processes including T-cell activation, the proliferation of costimulated T-cells, as well as the generation of cytolytic T-cells. CD70 on T cells provides costimulatory signals that are required for T cell proliferation, clonal expansion and the promotion of effector T cell formation.

Reconstitution Instructions: Reconstitute in sterile deionized water to a concentration of 100 µg/ml.

NCBI Gene Symbol: CD70

Gene ID: 21948

NCBI Accession: O55237