BioVision Proteins
Human CellExp™ CD27 / TNFRSF7, Fc Tag, Mouse Recombinant
- SKU:
- P1406-50
Description
Human CellExp™ CD27 / TNFRSF7, Fc Tag, Mouse Recombinant is available at Gentaur for Next week delivery.
Member of Tumor necrosis factor receptor superfamily, play a role in survival of activated T-cells and in apoptosis through association with SIVA1.
Biomolecule/Target:
Alternates names: CD27, TNFRSF7, S152, T14, Tp55
Synonyms: CD27, TNFRSF7, S152, T14, Tp55
Background Information: CD Antigen CD27 is also known as Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), which belongs to TNF-receptor superfamily. CD27 / TNFRSF7 is found in most T-lymphocytes. CD27 / TNFRSF7 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-κB and MAPK8/JNK. CD27 has been shown to interact with SIVA1, TRAF2 and TRAF3.
Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.
NCBI Gene Symbol: Cd27
Gene ID: 21940
NCBI Accession: P41272-1
Additional Information
Size: |
50 µg |
Adwords: |
False |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Murine |
Recombinant: |
True |
Source: |
HEK 293 cells |
Purity by SDS-PAGE: |
>95% |
Assay: |
SDS-PAGE |
Endotoxin Level: |
Less than 0.1 EU per μg by the LAL method |
Activity (Specifications/test method): |
Immobilized Mouse CD27, Mouse IgG2a Fc Tag at 2 μg/mL (100 μL/well) can bind Biotinylated Mouse CD70, His Tag, Avi Tag with a linear range of 1-16 ng/m. Immobilized Mouse CD27, Mouse IgG2a Fc Tag at 2 μg/mL (100 μL/well) can bind Biotinylated Human C |
Molecular Weight: |
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 45.1 kDa. The protein migrates as 55-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Appearance: |
Lyophilized powder |
Handling: |
Centrifuge the vial prior to opening. |