BioVision Proteins
Human CellExp™ GITR Ligand / TNFSF18 Fc Tag, Mouse recombinant
- SKU:
- P1126-50
Description
Human CellExp™ GITR Ligand / TNFSF18 Fc Tag, Mouse recombinant is available at Gentaur for Next week delivery.
Tumor necrosis factor receptor superfamily member 18
Biomolecule/Target: Tnfsf18
Alternates names: TNFSF18, AITRL, TL6, hGITRL, GITR Ligand
Synonyms: TNFSF18, AITRL, TL6, hGITRL, GITR Ligand
Background Information: Tumor necrosis factor ligand superfamily member 18 (TNFSF18) is also known as Glucocorticoid - induced TNF-related ligand (GITRL or GITR Ligand), Activation - inducible TNF - related ligand (AITRL), which belongs to the tumor necrosis factor family. TNFSF18 is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 / GITRL is up-regulated after stimulation by bacterial lipopolysaccharides (LPS). TNFSF18 Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. TNFSF18 / GITR Ligand is important for interactions between activated T-lymphocytes and endothelial cells. TNFSF18 also mediates activation of NF-kappa-B.
Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.
NCBI Gene Symbol: Tnfsf18
Gene ID: 240873
NCBI Accession: Q7TS55
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Mouse |
Recombinant: |
Yes |
Source: |
HEK 293 cells |
Purity by SDS-PAGE: |
> 95% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
< 1.0 EU per/μg |
Activity (Specifications/test method): |
Measured by its binding ability in a functional ELISA. |
Biological activity: |
Immobilized Mouse GITR, His Tag at 10μg/mL (100 μL/well) can bind Mouse GITR Ligand, Fc Tag with a linear range of 0.007-0.256 μg/mL. |
Results: |
N/A |
Molecular Weight: |
41.4 kDa |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |