CRIM1 Antibody (CT)

CRIM1 Antibody (CT)is available at Gentaur for Next week Delivery.

Description: CRIM1 (cysteine-rich motor neuron 1), a glycosylated type I transmembrane protein, plays a role in tissue development i.e. capillary formation and maintenance during angiogenesis. It contains an N-terminal IGF-binding protein-like motif and six von Willebrand-like cysteine-rich repeats (CRRs) in its extracellular domain. CRIM1 interacts with BMP4 and BMP7 via the CRRs and functions as an antagonist. CRIM1 is developmentally expressed in a number of tissues including the pancreas, kidney, placenta, brain and blood vessels. CRIM1 may participate in CNS and placental development by interacting with growth factors involved in motor neuron differentiation and survival.

Immunogen Sequence:CRIM1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human Crim1.

Target Alternative Name:Cysteine rich transmembrane BMP regulator 1 (chordin-like), CRIM-1, Cysteine-rich motor neuron 1 protein, Cysteine-rich repeat-containing protein S52

Species Reactivities:Human

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Formulation:100 µg (1 mg/ml) in 1X PBS containing 0.02 % sodium azide.

Purification: Affinity chromatography purified via peptide column

Application:Western blot, ELISA

Positive Control:Western Blot: Jurkat cell lysate

Application And Usages:Western Blot: 1 - 2 μg/ml, ELISA. However, the optimal conditions should be determined individually.

Handling:The antibody solution should be gently mixed before use.