BDNF Antibody (CT)

BDNF Antibody (CT)is available at Gentaur for Next week Delivery.

Description: Neurotrophins function to regulate naturally occurring cell death of neurons during development. The prototype neurotrophin is nerve growth factor (NGF), originally discovered in the 1950s as a soluble peptide promoting the survival of, and neurite outgrowth from, sympathetic ganglia. Three additional structurally homologous neurotrophic factors have been identified. These include brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3) and neurotrophin-4 (NT-4) (also designated NT-5). These various neurotrophins stimulate the in vitro survival of distinct, but partially overlapping, populations of neurons. The cell surface receptors through which neurotrophins mediate their activity have been identified. For instance, the Trk A receptor is the preferential receptor for NGF, but also binds NT-3 and NT-4. The Trk B receptor binds both BDNF and NT-4 equally well, and binds NT-3 to a lesser extent, while the Trk C receptor only binds NT-3.

Immunogen Sequence:This BDNF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-236 amino acids from the C-terminal region of human BDNF.

Target Alternative Name:BDNF; Brain-derived neurotrophic factor; Abrineurin

Species Reactivities:Human

Tag Line:Polyclonal Antibody to detect BDNF in human samples

Formulation:100 µl of antibody in PBS with 0.09% (W/V) sodium azide

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Application:Western blot, IHC

Positive Control:Western blot: CEM cell line, IHC: human brain tissue, FACS: CEM cells, IF: NCI-H460 cells

Application And Usages:Western blot: ~1:1000, IHC: ~1:10–1:50, IF: ~1:10–1:50, FC: ~1:10–1:50.

Handling:The antibody solution should be gently mixed before use.