LDHA Antibody (CT)

(No reviews yet) Write a Review
SKU:
6735-100
€245
Frequently bought together:

Description

LDHA Antibody (CT)is available at Gentaur for Next week Delivery.

Description: L-Lactate dehydrogenase A chain (LDHA) is a member of the LDH/MDH superfamily and LDH family. It catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA is localized primarily in muscle tissue and is part of the lactate dehydrogenase family. Mutations in LDHA have been linked to exertional myoglobinuria. LDH1 is decreased in essential thrombocythemia. LDHA is induced through a non-genomic pathway of estrogen action. Reduction in LDH-A activity results in stimulation of mitochondrial respiration and decrease of mitochondrial membrane potential. Mutations in LDHA have been associated with in LDHA are the cause of glycogen storage disease type 11 (GSD11) which is a metabolic disorder that results in exertional myoglobinuria, pain, cramps and easy fatigue.

Immunogen Sequence:This LDHA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 204-232 amino acids from the C-terminal region of human LDHA.

Target Alternative Name:LDHA; L-lactate dehydrogenase A chain; Cell proliferation-inducing gene 19 protein; LDH muscle subunit; Renal carcinoma antigen NY-REN-59.

Species Reactivities:Human. Predicted cross reactivity with monkey samples.

Tag Line:Polyclonal Antibody to detect LDHA in human samples

Formulation:100 µl of antibody in PBS with 0.09% (W/V) sodium azide

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Application:Western blot, IHC, IF.

Positive Control:Western blot: MDA-MB231 cell lysate, IHC: human hepatocarcinoma, IF: A375 cells

Application And Usages:Western blot: ~1:1000, IHC: ~1:10–1:50, IF: ~1:10-1:50.

Handling:The antibody solution should be gently mixed before use.

View AllClose

Additional Information

Size:
100 μl
Antibody Target:
LDHA
Category:
LDHA
Lot Number:
9E016735
Host:
Rabbit
Antibody Type:
Polyclonal
Isotype:
Rabbit IgG
Accession Number:
P00338
Gene Id:
3939
Concentration:
N/A
Appearance:
Colorless liquid
Form:
Liquid
Storage Condition:
-20 °C
Shipping Condition:
gel pack
Shelf Life:
12 months
Country of Animal Origin:
USA
Country of Manufacture:
USA
Usage:
For Research Use Only! Not to be used in humans.
Western Blot Verified:
Verified
Immunocytochemistry Verified:
Verified
Immunofluorescence Verified:
Verified
Immunoprecipitation Verified:
Not Verified
ELISA Verified:
Not Verified
ChIP Verified:
Not Verified
Flow Cytometry Verified:
Not Verified
View AllClose

0 Reviews

View AllClose