SDF-1beta/CXCL12, feline recombinant

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SKU:
4389-50
€185
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Description

SDF-1beta/CXCL12, feline recombinant is available at Gentaur for Next week delivery.

A small cytokine strongly chemotactic for lymphocytes

Biomolecule/Target: SDF-1 beta

Alternates names: C-X-C motif chemokine 12, C-X-C motif chemokine 12, Intercrine reduced in hepatomas, Pre-B cell growth-stimulating factor

Synonyms: SDF1

Background Information: Stromal Derived Growth Factor-1beta (SDF-1beta), also called CXCL12, is one of two splice variants made by a wide variety of cells when stimulated by inflammatory cytokines such as, TNF, IL-1 or LPS. SDF-1β signals through the G protein-couple receptor, CXCR4, to recruit activated leukocytes. Human SDF-1β shares 100% identity to feline SDF-1β. Recombinant feline SDF-1beta is a non-glycosylated protein, comprised of 72 amino acids, with a molecular weight of 8.5 kDa.

Reconstitution Instructions: Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/mL, which can be further diluted into other aqueous solutions.

NCBI Gene Symbol: SDF1

Gene ID: 493806

NCBI Accession: O62657

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Feline
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥97%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
HPLC
Endotoxin Level:
<0.01 ng/μg
Activity (Specifications/test method):
N/A
Biological activity:
The activity is determined by its ability to chemoattract human T cells at 10 - 75 ng/ml.
Results:
10 - 75 ng/ml.
Molecular Weight:
8.5 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
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