Description
RSK3, Active is available at Gentaur for Next week delivery.
Involved in signal transduction
Biomolecule/Target:
Alternates names: RSK, ribosomal protein S6 kinase, 90kDa, polypeptide 2
Synonyms: RSK, ribosomal protein S6 kinase, 90kDa, polypeptide 2
Background Information: RSK3 is a member of the RSK (ribosomal S6 kinase) family that encodes a 733-amino-acid protein with a unique N-terminal region containing a putative nuclear localization signal (1). RSK3 mRNA is widely expressed and is activated by growth factors, serum and phorbol ester. Upon stimulation, RSK3 translocates to the cell nucleus and phosphorylates nuclear proteins. RSK3 can bind to ERK1/2 and this association increases the duration of RSK3 activation (2).
Reconstitution Instructions: N/A
NCBI Gene Symbol: RPS6KA2
Gene ID: 6196
NCBI Accession: NM_021135.
Additional Information
Size: |
5 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Recombinant: |
Yes |
Source: |
Baculovirus (Sf9 insect cells) |
Purity by SDS-PAGE: |
≥90% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
HPLC |
Endotoxin Level: |
N/A |
Activity (Specifications/test method): |
The specific activity of RSK3 was determined to be 131 nmol /min/mg as per activity assay protocol. |
Biological activity: |
N/A |
Results: |
N/A |
Molecular Weight: |
112.0 kDa |
Storage Temperature: |
-80°C |
Shelf Life: |
12 months |
Concentration: |
0.1mg/ml |
Appearance: |
Liquid |
Handling: |
Centrifuge the vial prior to opening. |