Description
TrkB, Active is available at Gentaur for Next week delivery.
A high affinity catalytic receptor for several neurotrophins
Biomolecule/Target:
Alternates names: TrkB, neurotrophic tyrosine kinase, receptor, type 2, GP145-TrkB, Neurotrophic tyrosine kinase receptor type 2, TrkB tyrosine kinase, Tropomyosin-related kinase B
Synonyms: TrkB, neurotrophic tyrosine kinase, receptor, type 2
Background Information: TRKB is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. TRKB is the high affinity catalytic receptor for several "neurotrophins", which are small protein growth factors that induce the survival and differentiation of distinct cell populations (1). TRKB is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway (2). Signalling through TRKB leads to cell differentiation. Mutations in the TRKB gene have been associated with obesity and mood disorders.
Reconstitution Instructions: N/A
NCBI Gene Symbol: TRKB/ NTRK2
Gene ID: 4915
NCBI Accession: NM_001018064.
Additional Information
Size: |
5 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Recombinant: |
Yes |
Source: |
Baculovirus (Sf9 insect cells) |
Purity by SDS-PAGE: |
≥80% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
HPLC |
Endotoxin Level: |
N/A |
Activity (Specifications/test method): |
The specific activity of TRKB was determined to be 74 nmol /min/mg as per activity assay protocol. |
Biological activity: |
N/A |
Results: |
N/A |
Molecular Weight: |
67.0 kDa |
Storage Temperature: |
-80°C |
Shelf Life: |
12 months |
Concentration: |
5µg/50 µl |
Appearance: |
Liquid |
Handling: |
Centrifuge the vial prior to opening. |