TrkB, Active

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SKU:
7758-5
$183
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Description

TrkB, Active is available at Gentaur for Next week delivery.

A high affinity catalytic receptor for several neurotrophins

Biomolecule/Target:

Alternates names: TrkB, neurotrophic tyrosine kinase, receptor, type 2, GP145-TrkB, Neurotrophic tyrosine kinase receptor type 2, TrkB tyrosine kinase, Tropomyosin-related kinase B

Synonyms: TrkB, neurotrophic tyrosine kinase, receptor, type 2

Background Information: TRKB is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. TRKB is the high affinity catalytic receptor for several "neurotrophins", which are small protein growth factors that induce the survival and differentiation of distinct cell populations (1). TRKB is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway (2). Signalling through TRKB leads to cell differentiation. Mutations in the TRKB gene have been associated with obesity and mood disorders.

Reconstitution Instructions: N/A

NCBI Gene Symbol: TRKB/ NTRK2

Gene ID: 4915

NCBI Accession: NM_001018064.

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Additional Information

Size:
5 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Recombinant:
Yes
Source:
Baculovirus (Sf9 insect cells)
Purity by SDS-PAGE:
≥80%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
HPLC
Endotoxin Level:
N/A
Activity (Specifications/test method):
The specific activity of TRKB was determined to be 74 nmol /min/mg as per activity assay protocol.
Biological activity:
N/A
Results:
N/A
Molecular Weight:
67.0 kDa
Storage Temperature:
-80°C
Shelf Life:
12 months
Concentration:
5µg/50 µl
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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