PKCeta, Active

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SKU:
7731-5
£135.37
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Description

PKCeta, Active is available at Gentaur for Next week delivery.

Phosphorylate a wide variety of protein targets

Biomolecule/Target:

Alternates names: PKC, PKC, Protein kinase C eta

Synonyms: PKC, PKC, Protein kinase C eta

Background Information: PKC eta is a member of the protein kinase C (PKC) family of serine- and threonine-specific protein kinases that can phosphorylate a wide variety of protein targets known to be involved in diverse cellular signaling pathways. PKC η is predominantly expressed in squamous cell epithelia and induces terminal differentiation of keratinocytes. PKC η that is endogenously expressed or overexpressed is found to associate with the cyclin E/cdk2/p21 complex in keratinocytes of mice and humans (1).

Reconstitution Instructions: N/A

NCBI Gene Symbol: PRKCH

Gene ID: 5583

NCBI Accession: P24723

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Additional Information

Size:
5 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Recombinant:
Yes
Source:
Baculovirus (Sf9 insect cells)
Purity by SDS-PAGE:
≥90%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
HPLC
Endotoxin Level:
N/A
Activity (Specifications/test method):
86 nmol phosphate incorporated into peptide substrate (ERMRPRKRQGSVRRRV) per minute per mg protein at 30°C for 15 minutes using a final concentration of 50 µM ATP (0.83 µCi/assay).
Biological activity:
N/A
Results:
N/A
Molecular Weight:
103.0 kDa
Storage Temperature:
-80°C
Shelf Life:
12 months
Concentration:
5µg/50 µl
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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