Description
PKCeta, Active is available at Gentaur for Next week delivery.
Phosphorylate a wide variety of protein targets
Biomolecule/Target:
Alternates names: PKC, PKC, Protein kinase C eta
Synonyms: PKC, PKC, Protein kinase C eta
Background Information: PKC eta is a member of the protein kinase C (PKC) family of serine- and threonine-specific protein kinases that can phosphorylate a wide variety of protein targets known to be involved in diverse cellular signaling pathways. PKC η is predominantly expressed in squamous cell epithelia and induces terminal differentiation of keratinocytes. PKC η that is endogenously expressed or overexpressed is found to associate with the cyclin E/cdk2/p21 complex in keratinocytes of mice and humans (1).
Reconstitution Instructions: N/A
NCBI Gene Symbol: PRKCH
Gene ID: 5583
NCBI Accession: P24723
Additional Information
Size: |
5 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Recombinant: |
Yes |
Source: |
Baculovirus (Sf9 insect cells) |
Purity by SDS-PAGE: |
≥90% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
HPLC |
Endotoxin Level: |
N/A |
Activity (Specifications/test method): |
86 nmol phosphate incorporated into peptide substrate (ERMRPRKRQGSVRRRV) per minute per mg protein at 30°C for 15 minutes using a final concentration of 50 µM ATP (0.83 µCi/assay). |
Biological activity: |
N/A |
Results: |
N/A |
Molecular Weight: |
103.0 kDa |
Storage Temperature: |
-80°C |
Shelf Life: |
12 months |
Concentration: |
5µg/50 µl |
Appearance: |
Liquid |
Handling: |
Centrifuge the vial prior to opening. |