Human Fibrinogen (PAD4 Citrullinated)

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SKU:
P1719-50
£135.37
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Description

Human Fibrinogen (PAD4 Citrullinated) is available at Gentaur for Next week delivery.

A critical factor in blood clotting, inflammation, and rheumatoid arthritis

Biomolecule/Target:

Alternates names:

Synonyms: Fib2; FGA; HEL-S-78p; FGB; FGG

Background Information: Fibrinogen is a glycoprotein complex composed of three different polypeptides (α, β, γ) that is cleaved by thrombin to form an insoluble fibrin matrix that acts as a plasma clotting factor. Cleavage products of fibrinogen and fibrin regulate cell adhesion and activate chemotaxis. Chronic inflammation can induce protein arginine deiminases (such as PAD2 and PAD4) to citrullinate fibrinogen, which has been associated with auto-antibodies in rheumatoid arthritis.

Reconstitution Instructions:

NCBI Gene Symbol:

Gene ID: α - 2243; β - 2244; γ - 2266

NCBI Accession: α - P02671; β - P02675; γ - P02679

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Additional Information

Size:
50 µg
Adwords:
False
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
False
Source:
Human plasma
Purity by SDS-PAGE:
≥ 95% by SDS-PAGE
Molecular Weight:
α - 2 isoforms at 95 kDa and 69.8 kDa
Storage Temperature:
-80°C
Shelf Life:
12 months
Appearance:
Liquid protein
Handling:
Centrifuge the vial prior to opening.
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