BioVision Proteins
Human Fibrinogen (PAD4 Citrullinated)
- SKU:
- P1719-50
Description
Human Fibrinogen (PAD4 Citrullinated) is available at Gentaur for Next week delivery.
A critical factor in blood clotting, inflammation, and rheumatoid arthritis
Biomolecule/Target:
Alternates names:
Synonyms: Fib2; FGA; HEL-S-78p; FGB; FGG
Background Information: Fibrinogen is a glycoprotein complex composed of three different polypeptides (α, β, γ) that is cleaved by thrombin to form an insoluble fibrin matrix that acts as a plasma clotting factor. Cleavage products of fibrinogen and fibrin regulate cell adhesion and activate chemotaxis. Chronic inflammation can induce protein arginine deiminases (such as PAD2 and PAD4) to citrullinate fibrinogen, which has been associated with auto-antibodies in rheumatoid arthritis.
Reconstitution Instructions:
NCBI Gene Symbol:
Gene ID: α - 2243; β - 2244; γ - 2266
NCBI Accession: α - P02671; β - P02675; γ - P02679
Additional Information
Size: |
50 µg |
Adwords: |
False |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
False |
Source: |
Human plasma |
Purity by SDS-PAGE: |
≥ 95% by SDS-PAGE |
Molecular Weight: |
α - 2 isoforms at 95 kDa and 69.8 kDa |
Storage Temperature: |
-80°C |
Shelf Life: |
12 months |
Appearance: |
Liquid protein |
Handling: |
Centrifuge the vial prior to opening. |
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