Human Fibrinogen (PAD4 Citrullinated)

Human Fibrinogen (PAD4 Citrullinated) is available at Gentaur for Next week delivery.

A critical factor in blood clotting, inflammation, and rheumatoid arthritis

Biomolecule/Target:

Alternates names:

Synonyms: Fib2; FGA; HEL-S-78p; FGB; FGG

Background Information: Fibrinogen is a glycoprotein complex composed of three different polypeptides (α, β, γ) that is cleaved by thrombin to form an insoluble fibrin matrix that acts as a plasma clotting factor. Cleavage products of fibrinogen and fibrin regulate cell adhesion and activate chemotaxis. Chronic inflammation can induce protein arginine deiminases (such as PAD2 and PAD4) to citrullinate fibrinogen, which has been associated with auto-antibodies in rheumatoid arthritis.

Reconstitution Instructions:

NCBI Gene Symbol:

Gene ID: α - 2243; β - 2244; γ - 2266

NCBI Accession: α - P02671; β - P02675; γ - P02679