Human CellExp™ TYRO3 / Dtk, Human recombinant

Human CellExp™ TYRO3 / Dtk, Human recombinant is available at Gentaur for Next week delivery.

A protein kinase superfamily member that regulates cell survival, migration and differentiation

Biomolecule/Target: TYRO3

Alternates names: UCHL3, Ubiquitin thioesterase L3

Synonyms: UCHL3, Ubiquitin thioesterase L3

Background Information: Tyrosine-protein kinase receptor TYRO3 is also known as Tyrosine-protein kinase BYK, DTK, RSE, SKY, TIF, which belongs to the protein kinase superfamily, Tyr protein kinase family and AXL/UFO subfamily. TYRO3 regulates many physiological processes including cell survival, migration and differentiation. TYRO3 activates the AKT survival pathway, including nuclear translocation of NF-kappa-B and up-regulation of transcription of NF-kappa-B-regulated genes. TYRO3 interacts (via N-terminus) with extracellular ligands TULP1 and GAS6 By similarity and also interacts with PIK3R1, this interaction increases PI3-kinase activity.

Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.

NCBI Gene Symbol: TYRO3

Gene ID: 7301

NCBI Accession: Q06418