Human CellExp™ SERPIN F1, human recombinant

Human CellExp™ SERPIN F1, human recombinant is available at Gentaur for Next week delivery.

Has a variety of prpperties including antiangiogenic, antitumorigenic, and neurotrophic properties

Biomolecule/Target: SERPIN F1

Alternates names: SERPINF1, Serpin F1, PEDF, PIG35, EPC-1

Synonyms: SERPINF1, Serpin F1, PEDF, PIG35, EPC-1

Background Information: Serpin F1 (SERPINF1) is also known as Pigment epithelium-derived factor (PEDF), Cell proliferation-inducing gene 35 protein (PIG35). Serpin F1 belongs to the serpin family. Serpin F1 is expressed in quiescent cells. PEDF has a variety of functions including antiangiogenic, antitumorigenic, and neurotrophic properties. Endothelial cell migration is inhibited by SERPINF1/ PEDF. PEDF / SERPINF1 suppresses retinal neovascularization and endothelial cell proliferation. PEDF is also responsible for apoptosis of endothelial cells either through the p38 MAPK pathway or through the FAS/FASL pathway. PEDF also displays neurotrophic functions.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.

NCBI Gene Symbol: SERPINF1

Gene ID: 5176

NCBI Accession: P36955