Human CellExp™ PD-L1 /CD274 /B7-H1, human recombinant

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SKU:
7429-50
€185
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Description

Human CellExp™ PD-L1 /CD274 /B7-H1, human recombinant is available at Gentaur for Next week delivery.

Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner.

Biomolecule/Target: PD-L1 /CD274 /B7-H1

Alternates names: PD-L1, CD274, B7-H1, PDCD1L1, PDCD1LG1

Synonyms: PD-L1, CD274, B7-H1, PDCD1L1, PDCD1LG1

Background Information: Programmed cell death 1 ligand 1 (PD-L1) is also known as cluster of differentiation (CD274) or B7 homolog 1 (B7-H1). It has been identified as the ligand for PD1/PDCD1 (Cat. No. 7498) and has been demonstrated to play a role in the regulation of immune r

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.

NCBI Gene Symbol: CD274

Gene ID: 29126

NCBI Accession: Q9NZQ7

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
HEK293 cells
Purity by SDS-PAGE:
?95%
Assay:
SDS-PAGE
Purity:
?90%
Assay 2:
HPLC
Endotoxin Level:
N/A
Activity (Specifications/test method):
Measured by its binding ability in a functional ELISA
Biological activity:
Immobilized Human PD-L1, His Tag at 5 ?g/mL (100 ?L/well) can bind Human PD-1, His Tag with a linear range of 0.15-1.25 ?g/mL.
Results:
N/A
Molecular Weight:
This protein is fused with polyhistidine tag at the C-terminus, has a calculated MW of 26.4 kDa. The predicted N-terminus is Phe 19. DTT-reduced Protein migrates as 35-40 kDa due to glycosylation.
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized
Handling:
Centrifuge the vial prior to opening.
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PD-L1 /CD274, Human Recombinant is available at Gentaur for Next week delivery. Biomolecule/Target: PD-L1 /CD274 /B7-H1 Alternates names: PD-L1, CD274, B7-H1, PDCD1L1, PDCD1LG1 Synonyms:...
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