Human CellExp™ MBL/MBL2, human recombinant

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SKU:
8018-20
£135.37
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Description

Human CellExp™ MBL/MBL2, human recombinant is available at Gentaur for Next week delivery.

>95% Pure, active, Human cell expressed MBL/MBL2/Mannose binding Lectin

Biomolecule/Target: MBL/MBL2

Alternates names: MBL, MBL2, MBP1, MBP-C, Collectin-1, COLEC1, HSMBPC, MBL2D, MBPD, Mannose binding Lectin

Synonyms: MBL, MBL2, MBP1, MBP-C, Collectin-1, COLEC1, HSMBPC, MBL2D, MBPD, Mannose binding Lectin

Background Information: Mannose-binding lectin (MBL) is also known as mannose-binding protein, mannan-binding protein (MBP), Mannose-binding protein C, Collectin-1 (COLEC1), MBL2, which belongs to the class of collectins in the C-type lectin superfamily. MBL contains one C-type lectin domain and one collagen-like domain. MBL has an oligomeric structure (400-700 kDa), built of subunits that contain three presumably identical peptide chains of about 30 kDa each. MBL is calcium-dependent lectin involved in innate immune defense. MBL binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. MBL binds to late apoptotic cells. MBL may bind DNA.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in PBS, pH 7.4. Do not vortex.

NCBI Gene Symbol: MBL2

Gene ID: 4153

NCBI Accession: P11226

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Additional Information

Size:
20 µg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
HEK 293 cells
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
< 1.0 EU per μg of the protein by the LAL method.
Activity (Specifications/test method):
Measured by its ability to bind with Mannan in a functional ELISA.
Biological activity:
Measured by its ability to bind with Mannan in a functional ELISA.
Results:
Measured by its ability to bind with Mannan in a functional ELISA.
Molecular Weight:
This protein is fused with 6×His tag at the C-terminus, has a calculated MW of 24.8 kDa. The predicted N-terminus is Glu 21. DTT-reduced Protein migrates as 30-33 kDa.
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized
Handling:
Centrifuge the vial prior to opening.
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