BioVision Proteins
Human CellExp™ MBL/MBL2, human recombinant
- SKU:
- 8018-20
Description
Human CellExp™ MBL/MBL2, human recombinant is available at Gentaur for Next week delivery.
>95% Pure, active, Human cell expressed MBL/MBL2/Mannose binding Lectin
Biomolecule/Target: MBL/MBL2
Alternates names: MBL, MBL2, MBP1, MBP-C, Collectin-1, COLEC1, HSMBPC, MBL2D, MBPD, Mannose binding Lectin
Synonyms: MBL, MBL2, MBP1, MBP-C, Collectin-1, COLEC1, HSMBPC, MBL2D, MBPD, Mannose binding Lectin
Background Information: Mannose-binding lectin (MBL) is also known as mannose-binding protein, mannan-binding protein (MBP), Mannose-binding protein C, Collectin-1 (COLEC1), MBL2, which belongs to the class of collectins in the C-type lectin superfamily. MBL contains one C-type lectin domain and one collagen-like domain. MBL has an oligomeric structure (400-700 kDa), built of subunits that contain three presumably identical peptide chains of about 30 kDa each. MBL is calcium-dependent lectin involved in innate immune defense. MBL binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. MBL binds to late apoptotic cells. MBL may bind DNA.
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in PBS, pH 7.4. Do not vortex.
NCBI Gene Symbol: MBL2
Gene ID: 4153
NCBI Accession: P11226
Additional Information
Size: |
20 µg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
HEK 293 cells |
Purity by SDS-PAGE: |
≥95% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
< 1.0 EU per μg of the protein by the LAL method. |
Activity (Specifications/test method): |
Measured by its ability to bind with Mannan in a functional ELISA. |
Biological activity: |
Measured by its ability to bind with Mannan in a functional ELISA. |
Results: |
Measured by its ability to bind with Mannan in a functional ELISA. |
Molecular Weight: |
This protein is fused with 6×His tag at the C-terminus, has a calculated MW of 24.8 kDa. The predicted N-terminus is Glu 21. DTT-reduced Protein migrates as 30-33 kDa. |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |