Description
Human CellExp™ Lipoprotein Lipase, Human Recombinant is available at Gentaur for Next week delivery.
Involved in the hydrolysis of triglycerides of circulating chylomicrons and very low density lipoproteins
Biomolecule/Target: LPL
Alternates names: Lipoprotein lipase, LPL, LIPD, HDLCQ11
Synonyms: Lipoprotein lipase, LPL, LIPD, HDLCQ11
Background Information: LPL is a lipoprotein lipase, which is expressed in the heart, muscle, and adipose tissue. LPL acts as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Type I hyperlipoproteinemia is a result of severe mutations which cause LPL deficiency, whereas less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism. Lipoprotein lipase (LPL) is a fundamental enzyme in plasma triglyceride hydrolysis and is secreted by macrophages in the subendothelial space. LPL also promotes the development of atherosclerosis through facilitation of monocyte adhesion to endothelial cells, stimulation of tumor necrosis factor alpha (TNF) secretion and induction of vascular smooth muscle cell proliferation.
Reconstitution Instructions: Reconstitute in sterile deionized water to a concentration of 0.5 mg/ml
NCBI Gene Symbol: LPL
Gene ID: 4023
NCBI Accession: P06858
Additional Information
Size: |
10 µg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
HEK 293 cells |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
N/A |
Activity (Specifications/test method): |
N/A |
Biological activity: |
N/A |
Results: |
N/A |
Molecular Weight: |
51.8 kDa |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |