Human CellExp™ Lipoprotein Lipase, Human Recombinant

Human CellExp™ Lipoprotein Lipase, Human Recombinant is available at Gentaur for Next week delivery.

Involved in the hydrolysis of triglycerides of circulating chylomicrons and very low density lipoproteins

Biomolecule/Target: LPL

Alternates names: Lipoprotein lipase, LPL, LIPD, HDLCQ11

Synonyms: Lipoprotein lipase, LPL, LIPD, HDLCQ11

Background Information: LPL is a lipoprotein lipase, which is expressed in the heart, muscle, and adipose tissue. LPL acts as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Type I hyperlipoproteinemia is a result of severe mutations which cause LPL deficiency, whereas less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism. Lipoprotein lipase (LPL) is a fundamental enzyme in plasma triglyceride hydrolysis and is secreted by macrophages in the subendothelial space. LPL also promotes the development of atherosclerosis through facilitation of monocyte adhesion to endothelial cells, stimulation of tumor necrosis factor alpha (TNF) secretion and induction of vascular smooth muscle cell proliferation.

Reconstitution Instructions: Reconstitute in sterile deionized water to a concentration of 0.5 mg/ml

NCBI Gene Symbol: LPL

Gene ID: 4023

NCBI Accession: P06858