BioVision Products
Human CellExp™ Renin, Human Recombinant
- SKU:
- 6300-50
Description
Human CellExp™ Renin, Human Recombinant is available at Gentaur for Next week delivery.
An aspartyl protease specific for angiotensinogen.
Biomolecule/Target:
Alternates names: Angiotensinogenase, REN.
Synonyms: Angiotensinogenase, REN.
Background Information: Renin is a highly specific endopeptidase with the known function of generating angiotensin I from angiotensinogen in the plasma. This enzymatic reaction with the particular substrate angiotensinogen initiates a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. Prorenin is a glycosylated aspartic protease that consists of 2 homologous lobes and is the precursor of renin. Prorenin exhibits much lower level of enzymatic activity relative to activated renin. BioVision’s active human renin is produced from the pro-form prorenin by removing the 43 amino acid N-terminal pro-segment with trypsin
Reconstitution Instructions: N/A
NCBI Gene Symbol: REN
Gene ID: 5972
NCBI Accession: P00797
Additional Information
Size: |
50 μg |
Adwords: |
False |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
True |
Source: |
HEK 293 cells |
Purity by SDS-PAGE: |
≥95% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
N/A |
Activity (Specifications/test method): |
The specific activity is > 20 U/mg. The specific activity of active Renin was assayed using BioVision’s Renin Activity Fluorometric Assay Kit (Catalog # K800). |
Biological activity: |
N/A |
Results: |
N/A |
Molecular Weight: |
43 kDa (C terminal 8×His tag) |
Storage Temperature: |
-20ºC |
Shelf Life: |
12 months |
Appearance: |
Lyophilized powder |
Handling: |
Centrifuge the vial prior to opening. |