BioVision Products
Human CellExp™ Kallikrein-3, human recombinant
- SKU:
- 7415-10
Description
Human CellExp™ Kallikrein-3, human recombinant is available at Gentaur for Next week delivery.
Has important applications in the diagnosis of prostate cancer.
Biomolecule/Target: Kallikrein-3
Alternates names: PSA, KLK3, KLKB1, Kallikrein-3, APS, KLK2A1, PSA, Hk3, Seminin, Semenogelase
Synonyms: PSA, KLK3, KLKB1, Kallikrein-3, APS, KLK2A1, PSA, Hk3, Seminin, Semenogelase
Background Information: Kallikrein-3 (KLK3) is also known as Prostate-specific antigen (PSA), APS, Gamma-seminoprotein (Seminin), P-30 antigen, Semenogelase, is a glycoprotein enzyme, is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. The preferential cleavage site of KLK3 is “-Tyr-|-Xaa-“, the catalytic activity is inhibited by SERPINA5 and is strongly inhibited by Zn2+. KLK3 hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
NCBI Gene Symbol: KLK3
Gene ID: 3818
NCBI Accession: P03952
Additional Information
Size: |
10 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
HEK293 cells |
Purity by SDS-PAGE: |
≥92% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
<1 EU/μg by LAL method |
Activity (Specifications/test method): |
N/A |
Biological activity: |
Measured by its ability to cleave the colorimetric peptide substrate, Succinyl – Arg – Pro – Tyr – p – Nitroanilide (Suc-RPY-pNA). The specific activity is >60 pmoles / min / μg. |
Results: |
Measured by its ability to cleave the colorimetric peptide substrate, Succinyl – Arg – Pro – Tyr – p – Nitroanilide (Suc-RPY-pNA). The specific activity is >60 pmoles / min / μg. |
Molecular Weight: |
This protein is fused with 6×His tag at the C-terminus, has a calculated MW of 27.7 kDa. The predicted N-terminus is Ala 18. DTT-reduced Protein migrates as 36 kDa due to glycosylation. |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |