Human CellExp™ Kallikrein-11, human recombinant

Human CellExp™ Kallikrein-11, human recombinant is available at Gentaur for Next week delivery.

May serve as novel biomarkers for ovarian and prostate cancer and other diseases

Biomolecule/Target: Kallikrein-11

Alternates names: KLK11, Kallikrein-11, Hippostasin, hK11, PRSS20, TLSP

Synonyms: KLK11, Kallikrein-11, Hippostasin, hK11, PRSS20, TLSP

Background Information: Kallikrein 11 (KLK11) is also known as Hippostasin, Serine protease 20, Trypsin-like protease, PRSS20, TLSP, which belongs to the peptidase S1 family and Kallikrein subfamily. KLK11 contains one peptidase S1 domain. KLK11 is expressed in brain, skin and prostate. Isoform 1 is expressed preferentially in brain. Isoform 2 is expressed in prostate. Present in seminal plasma at concentrations ranging from 2 to 37 µg/mL (at protein level). Kallikrein 11 /KLK11 is a possible multifunctional protease and efficiently cleaves 'bz-Phe-Arg-4-methylcoumaryl-7-amide', a kallikrein substrate, and weakly cleaves other substrates for kallikrein and trypsin. KLK11 cleaves synthetic peptides after arginine but not lysine residues.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.

NCBI Gene Symbol: KLK11

Gene ID: 11012

NCBI Accession: Q9UBX7