BioVision Products
Human CellExp™ IL-28B, Human Recombinant
- SKU:
- 6472-50
Description
Human CellExp™ IL-28B, Human Recombinant is available at Gentaur for Next week delivery.
A cytokine mediating adaptive immune response
Biomolecule/Target:
Alternates names: Interleukin-28A, IL-28A, IFN-Lambda 2, Interferon-Lambda 2, Cytokine ZCYTO20, IL28A, IFNL2, ZCYTO20.
Synonyms: Human Cellexp Human Recombinant IL-28B
Background Information: IL-28B is a cytokine remotely related to type I interferons and the IL-10 family. Interleukin-28B, interleukin 28A (IL28A), and interleukin 29 (IL29) are 3 closely related cytokine genes which form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by these 3 genes can be induced by viral infection. All 3 cytokines interact with a heterodimeric class II cytokine receptor which consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
Reconstitution Instructions: Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
NCBI Gene Symbol: IFNL3
Gene ID: 282617
NCBI Accession: Q8IZI9
Additional Information
Size: |
50 µg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
China |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
Human 293 cell expressed |
Purity by SDS-PAGE: |
> 95% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
< 1.0 EU per 1 μg of protein |
Activity (Specifications/test method): |
N/A |
Biological activity: |
ED₅₀ is typically 0.1 to 1 ng/mL. The specific activity was determined by the dose-dependent protection of the cytopathic effect on A549 cells (human lung adenocarcinoma epithelial cell line) that were challenged with encephalomyocarditis (EMC) virus |
Results: |
0.1 to 1 ng/ml |
Molecular Weight: |
24 kDa, monomer, non-glycosylated |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |