Human CellExp™ GM-CSF R alpha, Human Recombinant

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SKU:
P1380-50
£135.37
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Description

Human CellExp™ GM-CSF R alpha, Human Recombinant is available at Gentaur for Next week delivery.

Transduces signal for proliferation, differentiation, and functional activation of hematopoietic cells.

Biomolecule/Target: GM-CSF R alpha

Alternates names: GM-CSF R alpha, GM-CSF-R-alpha, GMCSFR-alpha, GMR-alpha, CSF2RA, CSF2R, CSF2RY, CDw116, CD116

Synonyms: GM-CSF R alpha, GM-CSF-R-alpha, GMCSFR-alpha, GMR-alpha, CSF2RA, CSF2R, CSF2RY, CDw116, CD116

Background Information: GM-CSF R alpha(Granulocyte-macrophage colony-stimulating factor receptor subunit alpha) is also known as CSF2RA, CD116, GMR-alpha. Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. Hereditary pulmonary alveolar proteinosis (hPAP) is a rare disorder of pulmonary surfactant accumulation and hypoxemic respiratory failure caused by mutations in CSF2RA (encoding the granulocyte/macrophage colony-stimulating factor [GM-CSF] receptor α-chain [CD116]), which results in reduced GM-CSF-dependent pulmonary surfactant clearance by alveolar macrophages.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile deionized water, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. It is recommended to store at -20°C.

NCBI Gene Symbol: CSF2RA

Gene ID: 1438

NCBI Accession: P15509

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Additional Information

Size:
50 µg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
VRAI
Source:
HEK 293 cells
Purity by SDS-PAGE:
>95% as determined by SDS-PAGE
Endotoxin Level:
Less than 1.0 EU per μg by the LAL method.
Molecular Weight:
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 36.4 kDa. The protein migrates as 60-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation
Storage Temperature:
-20°C
Shelf Life:
12 months
Appearance:
Lyophilized powder
Handling:
Centrifuge the vial prior to opening.
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