BioVision Products
Human CellExp™ M-CSF, Human Recombinant
- SKU:
- 6455-50
Description
Human CellExp™ M-CSF, Human Recombinant is available at Gentaur for Next week delivery.
A hematopoietic growth factor
Biomolecule/Target: M-CSF
Alternates names: Macrophage Colony Stimulating Factor, CSF-1, Lanimostim, MCSF, MGC31930, M-CSF.
Synonyms: Human Cellexp Human Recombinant M-CSF
Background Information: Granulocyte/Macrophage Colony-Stimulating Factors (M-CSF) are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of granulocytes and monocytes-macrophages. M-CSF plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. It also plays an important role in innate immunity and in inflammatory processes by promoting the release of proinflammatory chemokines. M-CSF is also required for normal bone development and male/female fertility.
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS (pH 7.4). Do not vortex.
NCBI Gene Symbol: CSF1
Gene ID: 1435
NCBI Accession: P09603
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
Human 293 cell expressed |
Purity by SDS-PAGE: |
≥95% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
< 1.0 EU per 1 μg of protein |
Activity (Specifications/test method): |
N/A |
Biological activity: |
The EC50 is typically 0.5 to 4 ng/mL for this protein with specific activity determined by the dose dependent stimulation of the proliferation of murine M-NFS-60 cells (Mouse Myeloid Leukemia indicator cell line) |
Results: |
0.5 to 4 ng/ml |
Molecular Weight: |
This protein has 223 amino acids (Glu 33 - Arg 255) with a 6x-His tag at C-terminus, and a calculated MW of 26 kDa. The protein migrates to 35-45 kDa under reducing and non-reducing conditions (SDS-PAGE) due to glycosylation |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |