BioVision Proteins
Human CellExp™ PDGF R alpha / PDGFRA, Human Recombinant
- SKU:
- P1460-50
Description
Human CellExp™ PDGF R alpha / PDGFRA, Human Recombinant is available at Gentaur for Next week delivery.
Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells.
Biomolecule/Target:
Alternates names: PDGFRA, CD140A, PDGFR2, RHEPDGFRA, MGC74795
Synonyms: PDGFRA, CD140A, PDGFR2, RHEPDGFRA, MGC74795
Background Information: PDGFRA(platelet-derived growth factor receptor A), also termed PDGFRα(platelet-derived growth factor receptor α), is a receptor located on the surface of a wide range of cell types. This receptor binds to certain isoforms of platelet-derived growth factors (PDGFs) and thereby becomes active in stimulating cell signaling pathways that elicit responses such as cellular growth and differentiation. The receptor is critical for the development of certain tissues and organs during embryogenesis and for the maintenance of these tissues and organs, particularly hematologic tissues, throughout life. Mutations in the gene which codes for PDGFRA, are associated with an array of clinically significant neoplasms.
Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.
NCBI Gene Symbol: P16234
Gene ID: 5156
NCBI Accession: P16234-1
Additional Information
Size: |
50 µg |
Adwords: |
False |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
True |
Source: |
HEK 293 cells |
Purity by SDS-PAGE: |
>95% |
Assay: |
SDS-PAGE. |
Endotoxin Level: |
Less than 1.0 EU per μg by the LAL method. |
Molecular Weight: |
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 58.4 kDa. The protein migrates as 66-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Appearance: |
Lyophilized powder |
Handling: |
Centrifuge the vial prior to opening. |