BioVision Proteins
Human CellExp™ GITR / TNFRSF18, Human recombinant
- SKU:
- 9231-50
Description
Human CellExp™ GITR / TNFRSF18, Human recombinant is available at Gentaur for Next week delivery.
Tumor necrosis factor receptor superfamily member 18
Biomolecule/Target: GITR
Alternates names: AITR, GITR, TNFRSF18, CD358
Synonyms: AITR, GITR, TNFRSF18, CD358
Background Information: Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Reconstitution Instructions: Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/ml
NCBI Gene Symbol: TNFRSF19
Gene ID: 8784
NCBI Accession: Q9Y5U5-2
Additional Information
Size: |
50 µg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
HEK 293 cells |
Purity by SDS-PAGE: |
≥92% |
Assay: |
SDS-PAGE |
Purity: |
≥92% |
Assay 2: |
N/A |
Endotoxin Level: |
< 1 EU/μg |
Activity (Specifications/test method): |
Measured by its binding ability in a functional ELISA. |
Biological activity: |
Immobilized Human GITR/TNFRSF18, His Tag at 2 µg/mL (100 µL/well) can bind r-Human GITR Ligand /TNFSF18 with a linear range of 0.8-25 ng/mL. |
Results: |
N/A |
Molecular Weight: |
This protein is fused with a 6× His tag at C-terminus and has a calculated MW of 15.4 kDa. The protein migrates as 22-25 kDa in SDS-PAGE due to glycosylation. |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |