Human CellExp™ GITR Ligand / TNFSF18 Fc Tag, Mouse recombinant

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SKU:
P1126-50
€185
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Description

Human CellExp™ GITR Ligand / TNFSF18 Fc Tag, Mouse recombinant is available at Gentaur for Next week delivery.

Tumor necrosis factor receptor superfamily member 18

Biomolecule/Target: Tnfsf18

Alternates names: TNFSF18, AITRL, TL6, hGITRL, GITR Ligand

Synonyms: TNFSF18, AITRL, TL6, hGITRL, GITR Ligand

Background Information: Tumor necrosis factor ligand superfamily member 18 (TNFSF18) is also known as Glucocorticoid - induced TNF-related ligand (GITRL or GITR Ligand), Activation - inducible TNF - related ligand (AITRL), which belongs to the tumor necrosis factor family. TNFSF18 is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 / GITRL is up-regulated after stimulation by bacterial lipopolysaccharides (LPS). TNFSF18 Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. TNFSF18 / GITR Ligand is important for interactions between activated T-lymphocytes and endothelial cells. TNFSF18 also mediates activation of NF-kappa-B.

Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.

NCBI Gene Symbol: Tnfsf18

Gene ID: 240873

NCBI Accession: Q7TS55

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Mouse
Recombinant:
Yes
Source:
HEK 293 cells
Purity by SDS-PAGE:
> 95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
< 1.0 EU per/μg
Activity (Specifications/test method):
Measured by its binding ability in a functional ELISA.
Biological activity:
Immobilized Mouse GITR, His Tag at 10μg/mL (100 μL/well) can bind Mouse GITR Ligand, Fc Tag with a linear range of 0.007-0.256 μg/mL.
Results:
N/A
Molecular Weight:
41.4 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized
Handling:
Centrifuge the vial prior to opening.
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