Human CellExp™ DLL4, Mouse Recombinant

Human CellExp™ DLL4, Mouse Recombinant is available at Gentaur for Next week delivery.

Activates the Notch-1 and Notch-2 receptors

Biomolecule/Target: Dll4

Alternates names: Delta-like Protein 4, Delta 4

Synonyms: Delta-like Protein 4, Delta 4

Background Information: The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, pro-moting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.

Reconstitution Instructions: N/A

NCBI Gene Symbol: Dll4

Gene ID: 54485

NCBI Accession: Q9JI71