BioVision Proteins
Human CellExp™ DLL4, Mouse Recombinant
- SKU:
- P1163-50
Description
Human CellExp™ DLL4, Mouse Recombinant is available at Gentaur for Next week delivery.
Activates the Notch-1 and Notch-2 receptors
Biomolecule/Target: Dll4
Alternates names: Delta-like Protein 4, Delta 4
Synonyms: Delta-like Protein 4, Delta 4
Background Information: The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, pro-moting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.
Reconstitution Instructions: N/A
NCBI Gene Symbol: Dll4
Gene ID: 54485
NCBI Accession: Q9JI71
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Mouse |
Recombinant: |
Yes |
Source: |
HEK 293 cells |
Purity by SDS-PAGE: |
> 90% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
< 1.0 EU per/μg |
Activity (Specifications/test method): |
Measured by inhibition of adipogenesis of 3T3L-1 cells |
Biological activity: |
Inhibits adipogenesis of 3T3L-1 cells |
Results: |
N/A |
Molecular Weight: |
95 kDa |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Liquid |
Handling: |
Centrifuge the vial prior to opening. |