BioVision Products
Human CellExp™ Cystatin C, Human Recombinant
- SKU:
- 4878-50
Description
Human CellExp™ Cystatin C, Human Recombinant is available at Gentaur for Next week delivery.
A biomarker of kidney function
Biomolecule/Target:
Alternates names: Cystatin-3, Gamma-trace neuroendocrine basic polypeptide, Post-gamma-globulin
Synonyms: Human Recombinant Cystatin C
Background Information: Xeno-free Cystatin C HuXp (Cys-C) is expressed in human 293 cells as a monomer with an apparent molecular mass of 12 to 13 kDa. Native Cys-C in human urine is found in two different forms: one with pI 9.2 and the other with pI 7.8 by elimination of small basic peptides or amino acids from the N-terminal end of protein. Cystatin C has been studied for its role in predicting new onset or deteriorating cardiovascular disease. This cytokine is produced in a serum-free, chemically defined media.
Reconstitution Instructions: Reconstitute in sterile PBS.
NCBI Gene Symbol: CST4
Gene ID: 1472
NCBI Accession: P01036
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
Human 293 cells |
Purity by SDS-PAGE: |
≥95% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
HPLC |
Endotoxin Level: |
<0.1 ng/μg |
Activity (Specifications/test method): |
N/A |
Biological activity: |
The inhibitory function of Cystatin C on papin’s protease activity was measured by a colorimetric assay using L-BAPA as substrate. IC50 value was measured at 5 to 20 µg/mL (0.3 to 1.5 µM) with a range of 1.56 µg/mL to 50 µg/mL Cystatin C in presence |
Results: |
Typically 0.3 to 1.5 µM IC50. |
Molecular Weight: |
12-13 kDa |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized protein |
Handling: |
Centrifuge the vial prior to opening. |